Can the Tightening Serum be used on eyelids? Administrator August 30, 2017 20:52 The Tightening Serum is safe to use on eyelids, however, please avoid direct contact with the eyes. Related articles Instant Tightening & Restoring Serum How does the Instant Tightening & Restoring Serum work? Nourishing Night Cream How long do the effects of the Tightening Serum last? How do I apply the Tightening Serum? Comments 0 comments Please sign in to leave a comment.